Viewtiful Joe 2 is a 2D beat 'em up which combines side-scrolling and platforming. The player takes control of either of the characters Joe or Silvia to complete tasks within each stage, such as defeating enemies and bosses, and solving puzzles. Within Movieworld, Joe has "VFX Powers" such as Slow (similar to bullet-time), Mach Speed, and Zoom at his disposal to defeat the enemy. He is joined by girlfriend Silvia, who has also acquired VFX powers. However, Silvia has "Replay", which allows her to record and repeat an event three times in succession, instead of Joe's Mach Speed. The Replay power must be used wisely, as although it allow the player to do three times the amount of damage on an enemy, being hit while using it will incur three times the amount of damage to the player.[7]
During the game, the player utilize a gameplay mechanic called "Viewtiful Switch" in order to swap between Joe and Silvia at any time. The two characters share both their amount of health and the VFX meter. Holding the switch button down for a certain amount of time enables the two player characters to use a special attack involving the transformable robot Six Machine. At intervals between stages, V-Points can be spent to purchase new moves for either Joe or Silvia, or to improve their existing powers, which includes making Joe's Mach Speed more effective or upgrading Silvia's Desperados. V-Points can additionally be spent to give the player more maximum health, add extra lives, or be used to buy power-ups such as the VFX Turbo Charger, which slows the drainage of the VFX Gauge.
Aside from the main game, Viewtiful Joe 2 also contains an optional gameplay extra called the "36 Chambers of Viewtiful", a series of stages which test the player's skills. The objectives include defeating a set number of enemies or scoring a number of V-Points within a time limit, and dodging an onslaught of swords without dying.