Gameplay of all versions of the game is similar to The Bigs and The Bigs 2. The game contains all the MLB teams along with the all-star teams and fictional Nicktoons teams in standard quick play games 5 Nicktoons characters that have special abilities can be selected by each side. The game only contains 6 fictional Nicktoons ballparks (7 in the 3DS version) and 6 real-life MLB ballparks (8 in the 3DS version) compared to the full MLB ballpark lineups in both The Bigs games.