The game features gameplay similar to its predecessors NBA Jam and NBA Hangtime. Rather than typical 5 on 5 action, this game features 2 on 2 play with the ability to pick two players from any NBA team's starting line-up for the first half and can choose again for the second. The game introduces personal fouls for each shove on another player; after a certain number of fouls the opposing team gets a free throw. The game retains the series standard "on fire" feature. After a player makes three consecutive shots he becomes "on fire", which allows him to easily make shots from almost anywhere, as well as goaltend without penalty and push opponents without being charged a foul. Play otherwise is similar to NBA rules. The arcade version accommodates up to four players, as do the home versions produced for the Nintendo 64 and Dreamcast.
The players featured in the game include many of the most popular players of the particular year and era of the NBA season, but like the previous games in the arcade-style basketball series, many players were left out and each team has a limited number of players per position to choose from.