The game pitches a series of Marvel heroes and villains, including Venom, Wolverine, Iron Man, and Spider-Man against a series of original EA-created/owned characters. Combat is simplified in favor of allowing the player greater movement, and the game initially drew comparisons to Power Stone, Super Smash Bros. and Ehrgeiz as a result. The game featured Fatality-like finishing moves that could be triggered as soon as an opponent's health falls to 25% or lower.