Sector V of the KND are playing a videogame, when the Toilenator appears, and ties up everyone except for Numbuh 1, who was too distracted by a new simulator helmet Numbuh 2 designed.
After Numbuh 1 beats him and frees the team, they inform him that the Toilenator was, in fact real, just as Numbuh 86 calls in to tell everyone the organization's greatest foes have escaped from the Arctic Base Prison, and orders Sector V to recapture the villains, and transfer them to the KND Moonbase afterwards.
First on the list is Gramma Stuffum, who has taken over the Sprinkle Puff Donut Shoppe. After he defeats her, Numbuh 1 gets a call from Numbuh 4 informing him that the KND Treehouse is covered in snot. Meanwhile, someone steals the engine core from the Chuck Wagon.