The plot centers around Indy's search for the Staff of Moses, a journey which takes him to several locations including the Sudan, Panama, San Francisco, and Nepal. The game incorporates a linear structure which includes puzzles to solve, obstacles to clear, and enemies that must be defeated through hand-to-hand combat. As Indiana Jones, the player can interact with certain objects when prompted to and can utilize his bullwhip both in combat or to proceed in an area. Some levels also include sections where the gameplay revolves around using the environment around Indiana Jones to defeat enemies, and a shooting segment where the player's movement is restricted but is armed with Indy's sidearm and allowed to take cover and aim at enemies. Motion controls in the Nintendo versions (via the Wii Remote and Nunchuk, or the DS stylus, depending on the platform) allow the player to throw punches, use Indy's bullwhip, and perform a wide variety of actions.[3]
The Wii version of the game includes an exclusive co-op story mode (with Indy and Henry Jones Sr.) and unlockable version of the classic point and click adventure Indiana Jones and the Fate of Atlantis (also set in 1939). On the console versions, Big Head mode, Henry Jones Sr., Tuxedo Indy, and Han Solo from Star Wars are unlockable.[4]